|
antibiotics
Unnecessary and/or
inappropriate
antibiotics
prescriptions are estimated at 45 million per year.
Binding of
Δ9-THCA, Δ9-THC, CBN, CBD, and CBDA with
binding active site of SARS-CoV-2 Mpro had good docking scores
compared to reference compound a-ketoamide with similar binding pocket of
SARS-CoV-2 Mpro.
Δ9-THC and CBD showed a
slightly higher HOMO-LUMO energy gap in DFT calculations; these molecules are
stable with SARS-CoV-2 Mpro.
In MD simulations,
Δ9-THC- or CBD-SARS-CoV-2 Mpro complexes showed
better conformation stability than Δ9-THCA, CBN, and CBDA
complexes.
Δ9-THC or CBD bind to SARS-CoV-2
Mpro with stable conformations. |
1820 Eleven
doctors set up the US Pharmacopeia and record the first list of standard
drugs.
1911 US v. Johnson, the Supreme
Court rules that the 1906 Food and Drugs Act does not outlaw false medical
claims but only false and misleading statements about the ingredients or
identity of a drug.
1912 Congress passes the
Sherley Amendment to overcome the ruling in US v. Johnson.
The
Act outlaws labeling medicines with fake medical claims that is meant to trick
the buyer.
1937 Elixir Sulfanilamide, contains
the poisonous liquid, diethylene glycol, killing 107 persons, many of whom are
children.
1938 Congress passes The Federal Food,
Drug, and Cosmetic (FDC) Act, which requires that new drugs show safety before
selling.
1941 Nearly 300 deaths and injuries
result from the use of sulfathiazole tablets, an antibiotic, tainted with the
sedative, phenobarbital.
1950 Alberty Food
Products Co. v. US, a U.S. Court of Appeals rules that the directions for
use on a drug label must include the drug's purpose.
1951 Congress passes the Durham-Humphrey Amendment, which
defines the kinds of drugs that cannot be used safely without medical
supervision.
The amendment limits sale of these drugs to prescription
only by a medical professional.
All other drugs are to be available
without a prescription.
1952 Nationwide
investigation by FDA reveals that chloramphenicol, an antibiotic, caused nearly
180 cases of often deadly blood diseases.
1953
The Factory Inspection Amendment clarifies previous law and requires FDA to
give manufacturers written reports
of conditions seen during inspections and results of factory
samples.
Cipro
"Fluoroquinolone antibiotics
are commonly used to treat a variety of infections, including urinary tract,
respiratory tract, gastrointestinal tract, skin, bone, and joint infections.
First introduced in the 1980s to treat gram-negative bacterial
infections, the popularity of fluoroquinolone antibiotics has increased because
of their broad antimicrobial spectrum, multiple approved indications, and
favorable pharmacokinetics.
In fact, between 1995 and 2002,
fluoroquinolone prescribing tripled, making fluoroquinolones the class of
antibiotics most commonly prescribed to adults in the United States.
Despite their popularity, a number of adverse effects have been
attributed to fluoroquinolones, including adverse effects on musculoskeletal
tissues.
Fluoroquinolone-associated tendinopathy,
which was first reported in the literature in 1983, is a widely recognized
complication of fluoroquinolone use that eventually led the U.S. Food and Drug
Administration to add a black box warning label to all fluoroquinolones in
2008, citing increased risk of tendinitis and tendon rupture.
Fluoroquinolones exert
a toxic effect not only on tendons but also on cartilage, bone, and muscle.
Knowledge of the full spectrum of the negative effects of
fluoroquinolone antibiotics on the musculoskeletal system is currently
evolving, and much of the mechanistic nature of the
toxicity has not
yet been fully elucidated." - Musculoskeletal Complications of
Fluoroquinolones: Guidelines and Precautions for Usage in the Athletic
Population, Mederic M. Hall, MD, Jonathan T. Finnoff, DO, Jay Smith, MD,
Department of Physical Medicine and Rehabilitation, Mayo Clinic College of
Medicine, Mayo Clinic Sports Medicine Center, Rochester, MN
Although
all chemicals have side effects
most side effects are transient - they cease
when the medication is discontinued - this is NOT the case with Cipro or its
generic cousin Gentamicin !
Cipro, a 100% synthetic chemotherapeutic
chemical, works by interfering with bacterial DNA, preventing it from
replicating.
How can a synthetic chemical differentiate between
bacterial DNA and your DNA!?
Cipro is a fluoroquinolone (also called
"quinolone" or just "quin") class of chemicals.
Over HALF of all
fluoroquinolone antibiotics have been pulled from the market for their horrific
safety records - and those remaining (Cipro, Levaquin, Avelox and a few others)
are no safer!
Every single chemical in this class carries a "black box
warning" - the equivalent of a skull & crossbones.
Cipro's "black box warning" label makes it sound as if tendon rupture
is the worst possible scenario.
Cipro is actually capable of unleashing
an entire SYNDROME of systemic toxicity - "fluoroquinolone toxicity syndrome."
30-40 different adverse symptoms are suffered simultaneously and often
last a lifetime.
Cipro-induced
toxicity syndrome wreaks absolute havoc on every part of a person's body -
every tendon and joint in the body can become affected, every organ (including
the brain), peripheral
nervous system, dystonia,
muscle weakness,
autonomic dysfunction, vision damage including temporary blindness, retinal
tears and/or permanent double vision,
permanent tinnitus,
long lasting or permanent
central nervous system damage (including relentless insomnia, memory loss,
panic attacks, depersonalization,
psychosis), chronic fatigue, multiple
chemical sensitivities, severe muscle wasting, hair loss, skin changes,
Sjörgren's
syndrome, extensive dental damage …
Cipro is toxic to ALL
connective tissues !
Degeneration of the cartilage matrix in humans has
been observed following as few as two oral doses of Ciprofloxacin.
People have also suffered osteonecrosis (bone death) as a result of
taking this chemical.
Cipro is not even permitted for use in patients
under the age of 18 because it can interfere with the development of a child's
still-growing connective tissues. Cipro can render a top athlete of any age
completely crippled and unable to walk, let alone workout or compete ever
again.
Cipro's damage is cumulative.
Cipro is capable of
causing severe delayed reactions that don't manifest until long after you've
finished taking the chemical.
This means is that you could be
experiencing a potentially permanent, crippling reaction to the chemical but
have NO IDEA until it's too late! Your risk of spontaneously tearing or
rupturing a tendon continues for up to FIVE YEARS after you have ingested the
medication!
Cipro is also a
neurotoxin capable of
crossing the
blood-brain barrier and causing severe long-term neuropsychiatric side
effects.
These include
panic and
anxiety,
relentless insomnia, seizures,
confusion, depersonalization,
psychosis,
memory loss,
paranoia and hallucinations.
These
side effects can result from as little as ONE pill and persist for years or in
some instances even be permanent!
Cipro can calcify all of the nerves
in your teeth as well as permanently dry out your mouth, promoting extensive
tooth decay and/or tooth loss.
The vast majority of physicians are
completely ignorant about Cipro and its horrific and long-lasting side effects.
Most won't believe you when you tell them a prescription antibiotic has
caused your slew of sudden disabling health problems - even if your symptoms
match the ones listed right on the chemical's warning
label!
Doctors often
misdiagnose fluoroquinolone toxicity syndrome victims as having
autoimmune
disorders such as multiple sclerosis,
since many Cipro-induced ADR's mimic those of
autoimmune disorders.
Other favorite misdiagnosis include reflex sympathetic dystrophy (also
called chronic regional pain syndrome or CRPS),
fibromyalgia,
chronic fatigue
syndrome, scleroderma, Raynauld's syndrome, and Sjogren's.
There are natural plant based
antibiotics.
GentamicinRhett,
my cat, thought I was feeding him and jumped into the still wet insecticide so
I grabbed him and he landed a claw in my middle finger knuckle joint
(metacarpals/hamate) which became infected.
(Rhett passed away from
lung cancer - and I know he didn't
smoke!)
I ended up hospitalized.
First they give me a DPT shot
and then three Gentamicin intravenous drips with follow up oral doses of
Ciprofloxacin.
Gentamicin is an
aminoglycoside antibiotic composed of a mixture of related gentamicin
components and fractions and is used to treat many types of bacterial
infections.
It is synthesized by Micromonospora, a genus of
Gram-positive bacteria widely present in the environment (water and soil).
The drug binds avidly to certain tissues. Gentamicin can also be highly
nephrotoxic, particularly if multiple doses accumulate over a course of
treatment.
For this reason gentamicin is usually dosed by ideal body
weight.
Various formulae exist for calculating gentamicin dosage.
Also trough and peak serum levels of gentamicin are monitored during
treatment, generally before and after the third dose is infused.
Gentamicin, like other aminoglycosides, causes nephrotoxicity by
inhibiting protein
synthesis in renal cells.
This mechanism specifically causes
necrosis of cells in the proximal tubule, resulting in acute tubular necrosis
which can lead to acute renal failure.
Side effects of gentamicin
toxicity vary from patient to patient.
Side effects may become apparent
shortly after or up to months after gentamicin is administered.
Symptoms of gentamicin toxicity that I experienced included: balancing
difficulty, ringing in the ears (tinnitus); difficulty multi-tasking,
particularly when standing (anger breakdown at 149 over removal or leaving
door).
Psychiatric symptoms related to gentamicin that I experienced
included: confusion and disorientation.
Other side effects I
experienced included: loss of appetite, a severe intestinal condition
(Clostridium difficile-associated diarrhea enhanced with glyphosate) which may
occur during treatment or weeks to months after treatment has stopped.
Many medical practitioners freely administer gentamicin as an
antibiotic without advising patients of the severe and permanent potential
ramifications of its use.
Gentamicin is well known to be a cheap,
low-cost yet old medicine when compared with modern alternatives, and is
typically US$3-6 per dosage less than modern alternatives.
Many people
recover from gentamicin toxicity naturally over time if the drug is
discontinued, but they recover slowly and usually incompletely.
Sometimes the toxicity of gentamicin can still increase over months
after the last dose.
Upon cessation of gentamicin therapy symptoms such
as tinnitus and imbalance may become less pronounced.
Do not use
anti-diarrhea products or narcotic pain medications if you have any of the
following symptoms because these products may make them worse:
diarrhea,
abdominal or stomach pain/cramping, blood/mucus in your stool.
This is
not a complete list of possible side effects.
Levaquin
Erythromycin2004 Study published in New England Journal of Medicine
systematically documents a dramatic increase of cardiac arrest associated with erythromycin use.
"This study shows the need for continuing research on the safety of
older medicines, including how they interact with newer chemicals." -
researcher Wayne A. Ray, a professor of preventive medicine at Vanderbilt University School
of Medicine in Nashville.
"Nobody realized the magnitude of the
problem before." - Dr. Muhamed Sanc, cardiologist and director of the electro
cardiology laboratory at the University of Medicine and Dentistry of New Jersey
in Newark.
2008 30
million pounds of antibiotics are used in America each year.
Even
though 25 million pounds are used in
animal husbandry to
promote growth, only 2 million pounds of those antibiotics are used for
specific infections.
84% of salmonella is resistant to at least
one antisalmonella antibiotic.
54% of Campylobacter jejuni are
resistant to at least one anti-Campylobacter antimicrobial
agent.
Ketek(telithromycin)Telithromycin is a semi-synthetic erythromycin derivative.
It is forged by substituting a ketogroup for the cladinose sugar and
adding a carbamate ring in the lactone ring.
FDA approved Ketek,
patented by
Sanofi-Aventis, in 2004 to
treat severe infections.
The
FDA submitted clinical
trial data that key officials knew to be tainted by
scientific fraud
including fictitious patients.
Several users of Ketek experience liver
failure. |
|
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