|The hype about
'herd immunity' unfortunately creates a wall of hostility between those who
vaccinate and those who delay some vaccines, avoid certain vaccines, or quit
Since the beginning of vaccination, there is
little proof that vaccines are responsible for eradicating disease even when
'herd immunity' vaccination levels have been reached.
doctors rattle on about your unvaccinated neighbor being the biggest threat to
your child as if vaccination was the only way to avoid an illness or stay
To make matters worse, this intimidation to vaccinate is
played out in an environment where WHO and vaccine manufacturers have been
accused of scandalous
misrepresentations of disease risk, vaccine safety and
|Virion are also
known as "viral particles," and they are the means by which viral nucleic acids
are able to move and 'infect' living organisms.
Without the viral
particle (taxi) to carry around the virus DNA (passenger), it would be
harmless; in fact, viruses are often described as existing somewhere between
living and inanimate objects for this reason: they do not produce their own
energy, nor are transmissable without a living host.
acids, simply pathogenic strings of DNA or RNA, are not even alive, and can not
infect an organism without all the other components (proteins, lipids,
extra-viral nucleic acids) which are, technically, not viral in origin,
participating in the process.
"Influenza virion architecture includes
substantial quantities of host proteins as well as the viral protein." -
share stunning similarities to naturally occurring virus-like particles
produced by all living cells called exosomes.
Exosomes, like many
viruses (i.e. enveloped viruses) are enclosed in a membrane, and are within the
50-100 nanometer size range of virus.
They contain biologically active
molecules, such as proteins and lipids, as well as information-containing ones
like RNAs, very similar, to the types of contents you find in viral
(CoVs), enveloped positive-sense RNA viruses, are characterized by club-like
spikes that project from their surface, an unusually large RNA genome, and a
unique replication strategy.
Coronaviruses cause a variety of diseases
in mammals and birds ranging from enteritis in cows and pigs and upper
respiratory disease in chickens to potentially lethal human respiratory
Here we provide a brief introduction to coronaviruses
discussing their replication and pathogenicity, and current prevention and
We also discuss the outbreaks of the highly
pathogenic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the
recently identified Middle Eastern Respiratory Syndrome Coronavirus
positive RNA-enveloped viruses.
he first two human coronaviruses,
HCoV-229E and HCoV-OC43, were discovered in the mid-1960s.
They are a
well-known cause of the common cold.
The world epidemic of severe acute
respiratory syndrome human coronavirus (SARS-HCoV) in 20022003 reintroduced the
In 2004 and 2005, respectively, two new
coronaviruses were discovered: NL63 and HKU1.
The Coronaviridae family
is further subclassified into two genera: the alpha coronaviruses (HCoV-229E
and HCoV-NL63) and beta coronaviruses (HCoV-HKU1, HCoV-OC43, Middle East
respiratory syndrome [MERS]-HCoV, and SARS-HCoV).
causes mostly upper and at times lower respiratory tract infection,
community-acquired pneumonia, and also croup in children.
another coronavirus-related epidemic occurred, this time in the Middle East,
which led to the identification of the MERS-HCoV.
|The discovery of
the HCoV-NL63 and other novel human coronaviruses does not necessarily
represent a sudden increase in emerging infections by 'new' coronaviruses.
In the early 1960s, viral agents causing upper respiratory tract
infections were isolated from patients and were subsequently shown to be
coronaviruses by electron microscopy.
At least four of these were shown
to be serologically distinct from the known coronaviruses at the timeHCoV-NL63
has been shown to infect mainly children and the immunocommpromised, who
presented with either mild upper respiratory symptoms (cough, fever and
rhinorrhoea) or more serious lower respiratory tract involvement such as
bronchiolitis and croup, which was observed mainly in younger children.
HCoV-NL63 is the aetiological agent for up to 10% of all respiratory
Mode of Entry into the Cell: It is well documented that
SARS-CoV and HCoV-NL63 use the same receptor, angiotensin converting enzyme
(ACE)-2, for entry into the host cell.
SARS-CoV causes severe
respiratory distress, while HCoV-NL63 might lead to a mild respiratory
This was attributed to the ability of each virus
receptor-binding protein, spike or S protein, to bind to ACE-2 on the cell
It was found that the HCoV-NL63 S protein has a weaker
interaction with ACE-2 than the SARS-CoV S protein.
interaction with ACE-2 might partly explain the different pathological
consequences of infection by SARS-CoV and HCoV-NL63.
is expected to evolve with coronaviruses.
As for HCoV-NL63, the
possibility of the development of a recombinant virus variant is high because
of its high prevalence and the possibility of a recombination event through
Moreover, the virus is able to survive for up to seven
days in an aqueous solution and respiratory secretions and remains infective at
In heavily populated regions, direct person-to-person
transmission is considered the major route of HCoV-NL63
Donaldson and colleagues have reported the assembly of a
full-length infectious HCoV-NL63 clone, which will make the study of this virus
easier, improving our understanding of the role of each of the proteins encoded
by the HCoV-NL63 genome.
|Of the 674 Heath
Care Workers, 353 (52%) reported mild, self-limiting illnesses during the
period between the times when the first and second blood samples were
None of the 674 Heath Care Workers was shown to have IgG
antibody to SARS CoV.
|An outbreak of
severe acute respiratory syndrome (SARS) in humans, associated with a new
coronavirus (SARS-CoV), has been reported in Southeast Asia, Europe, and North
We have experimentally inoculated chickens and swine.
Both species are natural hosts for a number of viruses from the same
family as SARS-CoV (Coronaviridae).
The infectious bronchitis virus of
chickens, although distinct, groups genetically most closely with SARS-CoV
Swine can host several coronaviruses (hemagglutinating
encephalomyelitis virus, transmissible gastroenteritis virus [TGEV], and
porcine respiratory coronavirus [PRCV]).
Continuous cultures of porcine
turbinate cells (PT-K75) and primary chicken embryo epithelial kidney cells
supported SARS-CoV replication.
|The Army's premier
biological laboratory on Fort Detrick reported two breaches of containment
earlier this year, leading to the Centers for Disease and Control halting its
The U.S. Army Medical Research Institute of
Infectious Diseases announced Friday that it would restart its operations on a
limited scale. As it works to regain full operational status, more details
about the events leading to the shutdown are emerging.
findings report, obtained by the News-Post through a Freedom of Information Act
request, details some of the observations found during CDC inspections as well
as by USAMRIID employees who reported the issues.
of persistent viral infection is often associated with the selection of one or
more mutant viruses.
For example, it has been found that an intraleader
open reading frame (ORF) in genomic and subgenomic mRNA (sgmRNA) molecules is
selected during bovine coronavirus (BCoV) persistence which leads to
translation attenuation of the downstream ORF.
Here, we report the
unexpected identification of leaderless genomes, in addition to
leader-containing genomes, in a cell culture persistently infected with BCoV.
The discovery was made by using a head-to-tail ligation method that
examines genomic 5'-terminal sequences at different times
Functional analyses of the leaderless genomic RNA in a BCoV
defective interfering (DI) RNA revealed that (1) the leaderless genome was able
to serve as a template for the synthesis of negative-strand genome, although it
cannot perform replicative positive-strand genomic
RNA synthesis, and (2) the leaderless genome retained its function in
translation and transcription, although the efficiency of these processes was
Therefore, this previously unidentified leaderless genome is
associated with the attenuation of genome expression.
leaderless genome contributes to the establishment of persistent infection
remains to be determined.
| The date that PDCoV was
introduced into the United States is unknown.
The sequenced PDCoV
samples were from a similar geographic location, the 99.9%100% nt identity does
not correlate with the possible genetic diversity within the United States.
hypothesis would indicate that PDCoV has been an undiagnosed pathogen of
pigs in the United States and, like RVB, has been circulating there for an
extended period or that PDCoV might be a secondary infection to other enteric
Complete genome analysis of the US PDCoV strains showed that
they share 99.9%100% nt identity and a common ancestor with the only available
PDCoV sequences, the China PDCoV strains.
|Few threats to
human health have the potential to cause more impact than emerging zoonoses.
More than half of all known human pathogens have their origins in
It is the threat posed by these unknown, yet-to-emerge
pathogens that requires a reinvigorated and sustainable pathogen detection
network based on One Health principles to prevent a global widespread pandemic
resulting from a zoonotic agent.
|A newly identified
coronavirus that killed nearly 25,000 piglets in 2016-17 in China emerged from
horseshoe bats near the origin of the severe acute respiratory syndrome
coronavirus (SARS-CoV), which emerged in 2002 in the same bat species.
The new virus is named swine acute diarrhea syndrome coronavirus
It does not appear to infect people, unlike SARS-CoV which
infected more than 8,000 people and killed 774.
No SARS-CoV cases have
been identified since 2004.
The study investigators identified SARS-CoV
on four pig farms in Chinas Guangdong Province.
|Our studies show
that the deletion of group-specific genes from the coronavirus genome results
in live attenuated candidate vaccines against FIPV.
Our approach may
allow the development of vaccines against infections with other pathogenic
coronaviruses, including that causing severe acute respiratory syndrome in
|Ralph Baric, an
infectious-disease researcher at the University of North Carolina at Chapel
Hill, published a study on his team's efforts to engineer a virus with the
surface protein of the SHC014 coronavirus, found in horseshoe bats in China,
and the backbone of one that causes human-like severe acute respiratory
syndrome (SARS) in mice.
The hybrid virus could infect human airway
cells and caused disease in mice, according to the teams results, which were
published in Nature Medicine.
The results demonstrate the ability of
the SHC014 surface protein to bind and infect human cells, validating concerns
that this virusor other coronaviruses found in bat speciesmay be capable of
making the leap to people without first evolving in an intermediate host,
They also reignite a debate about whether that information
justifies the risk of such work, known as gain-of-function research.
the [new] virus escaped, nobody could predict the trajectory, Simon
Wain-Hobson, a virologist at the Pasteur Institute in Paris, told
invention provides a live, attenuated coronavirus comprising a variant
replicase gene encoding polyproteins comprising a mutation in one or more of
non-structural protein(s) (nsp)-10, nsp-14, nsp-15 or nsp-16.
coronavirus may be used as a vaccine for treating and/or preventing a disease,
such as infectious bronchitis, in a subject.
|The simplest way
to judge whether we have an exceptionally lethal disease is to look at the
Are more people dying than we would expect to die anyway
in a given week or month?
Statistically, we would expect about 51,000
to die in Britain this month.
At the time of writing, 422 deaths are
linked to Covid-19 so 0.8 per cent of that expected total.
On a global
basis, wed expect 14 million to die over the first three months of the year.
The worlds 18,944 coronavirus deaths represent 0.14 per cent of that
These figures might shoot up but they are, right now, lower than
other infectious diseases that we live with (such as flu).
that would, in and of themselves, cause drastic global
Initial reported figures from China and Italy suggested a
death rate of 5 per cent to 15 per cent, similar to 1918 Kansas
|Here we engineered
full, partially deleted (-29 nt), and fully deleted ORF8 into a SARS-CoV
infectious cDNA clone, strain Frankfurt-1.
Replication of the resulting
viruses was compared in primate cell cultures as well as Rhinolophus bat cells
made permissive for SARS-CoV replication by lentiviral transduction of the
human angiotensin-converting enzyme 2 receptor.
Cells from cotton rat,
goat, and sheep provided control scenarios that represent host systems in which
SARS-CoV is neither endemic nor epidemic.
Independent of the cell
system, the truncation of ORF8 (29 nt deletion) decreased replication up to
The effect was independent of the type I interferon
2010, large-scale outbreaks of diarrhea in suckling piglets have been reported
across China, and vaccination against PEDV has been relatively effective for
However, in February 2017, outbreaks of severe
diarrhea occurred in swine herds vaccinated against PEDV in Guangdong, China.
All ill pigs showed severe watery diarrhea, and their clinical onset
occurred a few days later than those infected with PEDV.
tests with reverse transcription PCR using specific primers for PEDV,
transmissible gastroenteritis virus, porcine group A rotavirus, or porcine
deltacoronavirus, none of these viruses could be detected.
Academy of Sciences approved the construction of a BSL-4 laboratory in 2003,
and the epidemic of SARS (severe acute respiratory syndrome) around the same
time lent the project momentum.
The lab was designed and constructed with
French assistance as part of a 2004 cooperative agreement on the prevention and
control of emerging infectious diseases.
The complexity of the project,
Chinas lack of experience, difficulty in maintaining funding and long
government approval procedures meant that construction wasnt finished until the
end of 2014.
The SARS virus has escaped from high-level containment
facilities in Beijing multiple times, notes Richard Ebright, a molecular
biologist at Rutgers University in Piscataway, New Jersey.
in 2017 that a SARS-like virus could escape a lab set up that year in Wuhan,
China, to study some of the most dangerous pathogens in the world.
a SARS-like coronavirus has infected more than 800 there, spread to at least 10
other countries and killed 25 in Wuhan and nearby provinces.
installed the first of a planned five to seven biolabs designed for maximum
safety in Wuhan in 2017, for the purpose of studying the most high-risk
pathogens, including the Ebola and the SARS viruses.
|The news that
COVID-19 bats were under research there means that a leak from the Wuhan
laboratory can no longer be completely ruled out.
A second institute in
the city, the Wuhan Centre for Disease Control which is barely three miles from
the market is also believed to have carried out experiments on animals such as
bats to examine the transmission of coronaviruses.
The Wuhan Institute,
which keeps more than 1,500 strains of deadly viruses, specializes in the
research of 'the most dangerous pathogens', in particular the viruses carried
Chinese officials decided to build the institute after the
country was ravaged by an outbreak of SARS in 2002 and 2003.
another kind of coronavirus, killed 775 people and infected more than 8,000
globally in an epidemic.
|In this study, we
used an IBV reverse genetics system based on the virulent YN strain of IBV, to
generate recombinant IBVs (rIBVs) in which the S gene or open reading frame
(ORF) 5a of the YN genome was replaced with the corresponding regions from the
attenuated YN strain (aYN).
Successfully rescued viruses were
characterized and subsequently investigated for pathogenicity and virulence in
ovo and in vivo.
The aim of this study was to identify viral components
critical for efficient replication and pathogenicity of gamma
enveloped, single-stranded RNA viruses that are distributed worldwide.
They include transmissible gastroenteritis virus (TGEV), porcine
epidemic diarrhea virus (PEDV), and the human coronaviruses severe acute
respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory
syndrome coronavirus (MERS-CoV).
Using a reverse-genetics system based
on CRISPR/Cas9 technology to construct a recombinant TGEV in which this
specific nsp1 motif was altered, we found that this mutation does not affect
virus replication in cell culture but significantly reduces TGEV pathogenicity
Alphacoronaviruses and betacoronaviruses harbor nonstructural
protein 1 (nsp1), which performs multiple functions in inhibiting antiviral
invention pertains to antigenic peptides of SARS-CoV.
Urbani contains several peptides recognized by sera derived from individuals
which have been and/or are still infected by SARS-CoV and recognized by control
sera derived from individuals which have not been infected by
Relevant binding of a peptide to a serum was calculated as
The average OD-value for each serum was calculated for the
spike protein (sum of OD-values of all peptides/total number of peptides).
Next, the standard deviation of this average was calculated.
The standard deviation was multiplied by 2 and the obtained value was
added to the average value to obtain the correction factor.
OD-value of each peptide was then divided by this correction factor.
a value of 0.9 or higher was found, then relevant binding was considered to be
present between the specific peptide and the respective serum.
clear for a skilled artisan that parts, variants or analogues of the peptides
and peptides comprising the identified peptides are also a part of the
|Event 201 pandemic
exercise, conducted on October 18, 2019, vividly demonstrated a number of
important gaps in pandemic preparedness as well as some of the elements of the
solutions between the public and private sectors that will be needed to fill
The Johns Hopkins Center for Health Security, World Economic
Forum, and Bill & Melinda Gates Foundation jointly propose the
|Labs around the
world are turning their sequencing machines, most about the size of a desktop
printer, to the task of rapidly sequencing the genomes of virus samples taken
from people sick with COVID-19.
The information is uploaded to a
website called NextStrain.org that shows how the virus is migrating and
splitting into similar but new subtypes.
|This shows that
there is limited genetic variation in the currently sampled viruses but more
recent ones are showing more divergence as is expected for fast evolving RNA
The lack of diversity is indicative of a relatively recent
common ancestor for all these viruses.
|The model was
created by assembling 3D parts together from related COVID-19 coronavirus
structures available in public databases.
The components used by the
developers include: Spike (S) protein (PDB code 6CRV) Envelope (E) protein (PDB
code 5X29) Membrane (M) protein (PDB code 3I6G).
The distribution of
these proteins on the surface of the virus was aligned by a random algorithm.
The overall representation surface protein density has been reduced to
help show S, E and M proteins.
The M lipid itself was generated using a
particle system to produce a random and organic result.
|Both the reused
and disposable ventilator systems had high bacterial contamination rates after
one week of use.
Disconnection of the ventilator systems should be
avoided during system operation to decrease
the risks of environmental
pollution and human exposure, especially for the disposable ventilator
vaccines are made in living cells (cell substrates). Some manufacturers are
investigating the use of new cell lines to make vaccines.
growth of cell lines ensures that there is a consistent supply of the same
cells that can yield high quantities of the vaccine. In some cases the cell
lines that are used might be tumorigenic, that is, they form tumors when
injected into rodents.
Some of these tumor-forming cell lines may
contain cancer-causing viruses that are not actively reproducing.
viruses are hard to detect using standard methods.
These latent, or
"quiet," viruses pose a potential threat, since they might become active under
vaccine manufacturing conditions.
|Among the myriad
statistics being published every day to induce the mass panic we're seeing, one
anomaly has been little commented upon.
One of the highest rates of
positive tests for coronavirus in the world, at 3,865 cases per million of the
population, is not Italy, with 1,906, not Spain, with 2,397, and definitely not
the UK, with 497, but Iceland.
With a population of only 340,680 thats
only 1,319 cases compared to over 115 thousand in Italy, 112 thousand in Spain,
and nearly 34 thousand in the UK; but proportionately, according to these
figures published on various websites recording the daily spread of the
pandemic, Iceland is the worst infected.
|The paper that
appears to have triggered the Trump administration's obsession with
hydroxychloroquine as a treatment for infection with the novel coronavirus has
received a statement of concern from the society that publishes the journal in
which the work appeared.
April 3, 2020: International Journal of
Antimicrobial Agents, states that the March 20 article, Hydroxychloroquine and
azithromycin as a treatment of Covid-19: results of an open-label
non-randomized clinical trial does not meet the [International Society of
Antimicrobial Chemotherapys] expected standard, especially relating to the lack
of better explanations of the inclusion criteria and the triage of patients to
ensure patient safety.
|The decision to
classify government coronavirus preparations in mid-January, followed by the
decision to coordinate the domestic response with the military and with
intelligence deserves considerable scrutiny, particularly given that at least
one federal agency, Customs and Border Patrol (CBP), will be given broad,
sweeping powers and will work closely with unspecified intelligence
partners as part of its response to a pandemics like
While the plans of the federal government remain classified,
recent reports have revealed that the military and intelligence communities now
working with the NSC to develop the governments coronavirus response have
anticipated a massive explosion in cases for weeks.
intelligence came to the conclusion in early February that coronavirus cases
would reach pandemic proportions domestically by the end of March.
National Center for Medical Intelligence (NCMI), coordinates closely with the
National Security Agency (NSA) to conduct medical SIGINT [signals
|Tony Fauci, a
leading member of the White House Coronavirus Task Force, is being promoted by
major US media such as CNN, MSNBC or the New York Times as the great expert on
all related to the Covid19 outbreak.
Tony Fauci has held the top post
at the NIAID in Washington for an astonishing 36 years.
In 1984 Robert
Gallo, working under Fauci, falsely announced that he had "discovered" the AIDS
Media was told that AIDS was the "public health threat of the
Gallo went on to make millions on his patented blood test for
HIV, despite the fact that the test was often giving false positives and did
not test directly for the alleged virus but for active antibodies, something
immunology practice said was not valid, as antibodies merely suggested a past
infection response and not necessarily presence of AHIV.
employing a multifaceted approach to the creation of a potential AIDS vaccine.
These approaches include the use of killed or attenuated virus,
purified natural or synthetic subunits of the virus, infectious recombinant
viruses, and anti-idiotypes.
The first clinical trial of a subunit AIDS
vaccine began in September 1987 at the National Institutes of Health (NIH).
|Even before you
know something works, at risk, you have to start producing it.
know it works, you can't say, it works, give me another six months.
are working with a variety of companies to take that risk.
take it with zika.
Same with sars.
That is what we are going to
push on is to be able to have it ready if, in fact, it works. the issue of
safety, something I want to make sure the American public understands.
There is safety associated, does the vaccine make you
There are diseases in which you vaccinate and get infected and
enhance the infection.
antiretroviral treatment and current prevention options have considerably
reduced HIV infections and AIDS-related deaths, a safe and effective vaccine is
needed to end the global AIDS pandemic expeditiously and sustainably, according
to a new commentary from Anthony S. Fauci, M.D., Director of the National
Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. National
Institutes of Health (NIH), and colleague Hilary D. Marston, M.D., M.P.H., in
The New England Journal of Medicine.
|When the World
Health Organization designated the coronavirus a pandemic extraordinary
privileges were conferred to US authorities.
March 11 Trump announced a
ban for the next 30 days on travelers flying from Europe to the United
The document states: Due to the distance from CDC Quarantine
Stations, some [CBP] locations will require areas designated for medical
segregation to safely detain travelers potentially infected with the pandemic
flu virus, thereby, helping prevent the spread of the virus to other detainees,
travelers, and CBP employees.
And: CBP Directors of Field Operations
and Chief Patrol Agents will jointly inventory their
detention and isolation
facilities, and identify other areas that may be utilized for these
purposes, e.g., tent cities with portable latrines.
|This July, we will
be celebrating the centennial anniversary of London's First International
Eugenics Conference of 1912.
One century later, on July 11, 2012, the
Bill & Melinda Gates Foundation (the largest private foundation in the
world) and the British government will co-host a new London conference on
eugenics with global coalition partners such as American abortion chain Planned
Parenthood, British abortion chain Marie Stopes International, and the United
Nations Populations Fund (UNFPA).
The only difference is that the July
2012 London conference will never acknowledge that eugenics is its driving
Hard eugenics is the
ideology that dare not speak its name.
But soft eugenics is based
on the same disturbing belief -- that government should spend its resources to
prevent the propagation of those whom the government believes to be detrimental
to society and economic growth.
And that should be deeply
efforts are a concern because apparently the only thing she and her partners
intend to cure with this campaign is pregnancy, which is not a disease.
One cant help but wonder what the $4.6 billion they already have raised
could do to bring effective medical care closer to those who need it rather
than simply preventing our children from being born.
hopefully realise that letting rich people decide on population size is a bad
coronavirus pneumonia (COVID-19) is an infectious acute respiratory infection
caused by the novel coronavirus.
The virus is a positive-strand RNA
virus with high homology to bat coronavirus.
In this study, conserved
domain analysis, homology modeling, and molecular docking were used to compare
the biological roles of certain proteins of the novel coronavirus.
results showed the ORF8 and surface glycoprotein could bind to the porphyrin,
At the same time, orf1ab, ORF10, and ORF3a proteins could
coordinate attack the heme on the 1-beta chain of hemoglobin to dissociate the
iron to form the porphyrin.
The attack will cause less and less
hemoglobin that can carry oxygen and carbon dioxide.
The lung cells
have extremely intense poisoning and inflammatory due to the inability to
exchange carbon dioxide and oxygen frequently, which eventually results in
ground-glass-like lung images.
patient age was 63 years old.
The mortality rate for all patients placed
on mechanical ventilation was 88.1%.
The case series documents
comorbidities among patients, with the most common being hypertension, obesity
Almost 42 percent of all patients hospitalized with
coronavirus were reportedly obese, with a body mass index (BMI) of more than or
Diabetes was found to be a prevalent pre existing condition, with
33.8 percent of coronavirus patients reported as being
for Damages: Fraud and Wrongful Death.
Filed suit against multiple
defendants including Life Care Centers of America, Inc.
The other named
defendants include Lake Vue Operations, LLC, LCCAs Vice President of Operations
West, and Kirklands Executive Director.
The suit was filed in the King
County Superior Court of Washington on April 10, 2020.
On April 13,
2020, CMS released guidance highlighting the flexibilities regarding patient
Transfers may be necessary to separate residents based on
whether they have tested positive or are otherwise suspected of having
When transfers are to be made to non-certified facilities,
State Agency approval is required.
COVID-19 Preparedness Checklist for Nursing
|UPDATE, April 28:
Here is a link to the most recent data for total deaths in the U.S. by week,
rather than by month, from the CDC.
The most recent week for which they
are reporting complete data is what they call 2020 Week 15, which appears to be
the week of April 5 to 11.
They report 55,905 total deaths that week.
If the normal number of non-coronavirus deaths per day in April is
7700, that would mean that a normal non-coronavirus week would be
So the number of excess deaths in that week is only about 2000.
Worldometers reports the number of Covid-19 deaths that week as
prevalence of SARS-CoV-2 antibodies in Santa Clara County implies that the
infection is much more widespread than indicated by the number of confirmed
Population prevalence estimates can now be used to calibrate
epidemic and mortality projections.
people in America weeks earlier than first thought, according to a new report
citing confirmation from the Centers for Disease Control and Prevention.
The first two deaths occurred on Feb. 6 and 17 in Santa Clara County,
California a tech hub that had previously considered March 9 its first death
death date the countys health department said in a statement late Tuesday.
This means the virus was introduced and circulating in our community
far earlier than we had previously known, said Dr. Sara Cody, director of
public health for Santa Clara County, during a briefing on Wednesday morning.
There was likely a significant level of the virus circulating in early
February and probably late January.
| Apr 8, 2020: With
over two dozen different molecular diagnostics now authorized by the FDA for
COVID-19, the field is beginning to see the first of a new group of tests aimed
at screening for people's immune responses to the disease and cataloguing past
infections instead of active ones.
While overall testing capacity of
any kind remains far short of meeting demand, antibody blood tests would
provide additional data on the spread of the novel coronavirus, and results
showing immunity could be used to give people an all-clear to leave quarantine
and return to work. Their accuracy would, of course, have to be paramountany
false positives could send unprotected people back into harms way.
researchers at the University of Oxford tasked with evaluating these
serological tests say theyre still weeks away from solid validation and that no
versions to date have performed well.
suspect the driving force in many gravely ill patients' downhill trajectories
is a disastrous overreaction of the immune system known as a cytokine
storm, which other viral infections are known to trigger.
Cytokines are chemical signaling molecules that guide a healthy immune
response; but in a cytokine storm, levels of certain cytokines soar far beyond
whats needed, and immune cells start to attack healthy tissues.
vessels leak, blood pressure drops, clots form, and catastrophic organ failure
can ensue. Some studies have shown elevated levels of these
inflammation-inducing cytokines in the blood of hospitalized COVID-19 patients.
The real morbidity and mortality of this disease is probably driven by
this out of proportion inflammatory response to the virus, says Jamie Garfield,
a pulmonologist who cares for COVID-19 patients at Temple University
|A new study in
China has found that the novel coronavirus has mutated into at least 30
The results showed that medical officials have
vastly underestimated the overall ability of the virus to mutate, in findings
that different strains have affected different parts of the world, leading to
potential difficulties in finding an overall cure.
|The World Health
Organization issued a warning Friday about coronavirus testing, saying there's
no evidence serological tests can show whether a person has immunity or is no
longer at risk of becoming reinfected.
These antibody tests will be
able to measure that level of serology presence, that level of antibodies, but
that does not mean that somebody with antibodies is immune, said Dr. Maria Van
Kerkhove, head of WHOs emerging diseases and zoonosis unit.
respirators do not work.
There have been extensive randomized
controlled trial (RCT) studies, and meta-analysis reviews of RCT studies, which
all show that masks and respirators do not work to prevent respiratory
influenza-like illnesses, or respiratory illnesses believed to be transmitted
by droplets and aerosol particles.
Furthermore, the relevant known
physics and biology, which I review, are such that masks and respirators should
It would be a paradox if masks and respirators worked, given
what we know about viral respiratory diseases: The main transmission path is
long-residence-time aerosol particles (< 2.5 µm), which are too fine
to be blocked, and the minimum-infective-dose is smaller than one aerosol
The present paper about masks illustrates the degree to which
governments, the mainstream media, and institutional propagandists can decide
to operate in a science vacuum, or select only incomplete science that serves
Such recklessness is also certainly the case with the
current global lockdown of over 1 billion people, an unprecedented experiment
in medical and political history.
presidency of George H.W. Bush in the early 1990s, something disturbing
unfolded at the U.S.' top biological warfare research facility at Fort Detrick,
Maryland. Specimens of highly contagious and deadly pathogens anthrax
and ebola among them had disappeared from the lab, at a time when lab
workers and rival scientists had been accused of targeted sexual and ethnic
harassment and several disgruntled researchers had left as a result.
internal Army inquiry in 1992 would reveal that one employee,
Lt. Col. Philip Zack, had been caught
on camera secretly entering the lab to conduct unauthorized research,
apparently involving anthrax, the Hartford Courant would later report.
Despite this, Zack would continue to do infectious disease research for
pharmaceutical giant Eli Lilly and would collaborate with the U.S. National
Institute of Allergy and Infectious Disease (NIAID) throughout the 1990s.
|One hundred forty
six homeless persons at a Boston shelter tested positive for the coronavirus
without showing any symptoms, concerning experts that the pandemic may be more
wide spread than originally thought.
The Pine Street Inn was following
up a small cluster of cases last week and tested 397 people to discover that
146 were confirmed to have the deadly flu-like virus, also known as COVID-19.
What was equally alarming to health officials was also learning that
100 per cent of the confirmed cases at the shelter had no symptoms.
surveillance firm founded by conservative billionaire Peter Thiel, has landed a
contract with the feds to build a database tracking the spread of the novel
coronavirus around the country.
Palantir data products will be primary,
or even core, to a Health and Human Services project called Protect Now and
will pull data from federal, state, and local governments, as well as
universities and medical facilities.
The purpose of the project is to
mitigate and prevent spread of the virus, an HHS spokesperson told the site.
Palantirs involvement is likely to raise eyebrows, as Thiel is both its
chairman and a prominent Donald Trump supporter who has pledged to support the
presidents re-election campaign.
He also reportedly was involved in
pushing Facebook, where he holds a board seat, to allow political lies in ads,
even setting up a meeting between Mark Zuckerberg and Trump at the White
Palantir, Prism, Facebook & The Industrial Surveillance
We have seen this kind of intense pressure on Aaron Swartz.
Immediately the story was no longer about government surveillance and
potential crimes but about 'crazy ol' Brown'.
Brown has been sitting in
jail ever since and the story was dropped until Snowden came along.
practices at the Centers for Disease Control and Prevention caused
contamination that rendered the nation's first coronavirus tests ineffective,
federal officials confirmed on Saturday.
Two of the three CDC
laboratories in Atlanta that created the coronavirus test kits violated their
own manufacturing standards.
CDC sent tests that did not work to nearly
all of the 100 state and local public health labs, according to the Food and
coronavirus testing expands in prisons, large numbers of inmates are showing no
symptoms. In four state prison systems Arkansas, North Carolina, Ohio
and Virginia 96% of 3,277 inmates who tested positive for the
coronavirus were asymptomatic, according to interviews with officials and
records reviewed by Reuters.
Thats out of 4,693 tests that included results on symptoms.
placebo-controlled trial in children showed that flu shots increased fivefold
the risk of acute respiratory infections caused by a group of noninfluenza
viruses, including coronaviruses.
|There is genetic
evidence suggestive of human tinkering in the genome, and there are news
stories suggesting the virus might have been developed either at the Wuhan
Institute of Virology or at the American virology lab at Fort Detrick.
There are even some suggestions that the American and Chinese
bioweapons labs may be working together, sharing samples and exchanging
The question of a laboratory origin for COVID is politically
explosive, so we expect a heavy hand restraining the science establishment.
Those of us seeking an honest answer, who have a little expertise, a
little horse sense, and a lot of patience, are left to sift through
information, misinformation, and disinformation in a politicized
| 2014 The Lugar
Center, a $161 million Pentagon-funded biolaboratory in Georgia's capital
Tbilisi, discovered coronaviruses in bats with presumably pandemic
2016 Eco Health Alliance, US scientists and USAID launched
the The Global Virome Project
2018 Pentagon launched a $2.9 million
program at the Lugar Center involving genetic studies on coronaviruses in 5,000
bats collected in Western Asia.
Eco Health Alliance received a $3.7
million grant from the US National Institute of Health (NIH) to collect and
study coronaviruses in bats in China from 2014 to 2019.
coronaviruses were similar to beta coronaviruses discovered in bats in Spain,
Italy, Bulgaria and to the pandemic SARS coronavirus with lethal outcome in
Amsterdam, China, Florida and Colorado.
US Defense Threat Reduction
Agency (DTRA) launches a $2.9 million project on bats and coronaviruses in
Western Asia with the Lugar Center being the local laboratory for this genetic
The duration of the program is 5 years and has been
implemented by the non-profit US organization Eco Health Alliance.
Rockefeller Foundation has long been supporting such projects.
foundation has even provided the dangerous Zika Virus for sale online for
Ironically, the project was presented at the
Rockefeller Foundations Conference Center in Bellagio, Italy which 4 years
later became the epicenter of the coronavirus pandemic in
| We present an
approach to encode medical history on a patient using the spatial distribution
of biocompatible, near-infrared quantum dots (NIR QDs) in the dermis.
QDs are invisible to the naked eye yet detectable when exposed to NIR
QDs with a copper indium selenide core and aluminum-doped zinc
sulfide shell were tuned to emit in the NIR spectrum by controlling
stoichiometry and shelling time.
The formulation showing the greatest
resistance to photobleaching after simulated sunlight exposure (5-year
equivalence) through pigmented human skin was encapsulated in microparticles
for use in vivo.
|In response to the
COVID-19 pandemic, QDX HealthID provides end-to-end visibility to support
testing and immunization, including authentication of patients, healthcare
providers and virus test kits.
search for a vaccine that can stop the AIDS virus has delivered yet another
The HIV vaccine that had moved furthest along in
human testing does not work, and the $104 million trial in
South Africa evaluating
it has been stopped early.
Theres absolutely no evidence of efficacy,
says Glenda Gray, who heads the study and is president of the South African
Medical Research Council (MRC).
Years of work went into this. Its a
|Using history as a
lens, it is possible to look at the current coronavirus crisis to see how the
long-standing agendas of ever-expanding mass surveillance and media censorship
are again getting a dramatic boost thanks to the chaos unleashed by the
Pentagons Defense Advanced Research Projects
Agency (DARPA) has remained largely out of sight and
out of mind for most
Americans, as their research projects are rarely covered by the mainstream
media and, when they are, their projects are often praised as
bringing science fiction movies to life.
|There is a
lot of speculation here. They have no experimental verification, Peter
Hotez, PhD, of the Texas Children's Hospital Center for Vaccine Development in
Houston, told the Los Angeles
In any case, as the investigators themselves noted,
increased transmissibility does not necessarily imply increased danger; a
sub-analysis in the report showed no rise in the risk of severe illness linked
to the mutated sequence, compared with its predecessor:
evidence of recombination between locally circulating strains, indicative of
multiple strain infections.
The mutation Spike D614G is of urgent
concern; it began spreading in Europe in early February, and when introduced to
new regions it rapidly becomes the dominant form.
Given Spikes vital
importance both in terms of viral infectivity and as an antibody target, we
felt an urgent need for an early warning pipeline to evaluate Spike pandemic
Our primary intent is to identify dynamically changing
patterns of mutation indicative of positive selection for Spike variants.
Also, because recombination is an important aspect of coronavirus
evolution (Graham and Baric, 2010; Li et al., 2020; Rehman et al., 2020), we
also set out to determine if whether recombination is playing a role in
SARS-CoV-2 pandemic evolution.
chronicle a three-stage
data pipeline (analysis of daily GISAID data, structural modeling of sites of
interest, and experimental evaluation) and the identification of several sites
of positive selection, including one (D614G) that may have originated either in
China or Europe, but begin to spread rapidly first in Europe, and then in other
parts of the world, and which is now the dominant pandemic form in many
Over 62 vaccine approaches are currently being explored, and
a wide variety of candidate SARS-CoV-2 vaccines are in
|Most of this
manuscript focuses on a particular mutant called D614G.
outside the field, thats a standard notation that translates as at amino acid
residue 614, take the existing amino acid (aspartic acid, single-letter code D)
and change it to a glycine (single-letter code G)
That change happens
through the triplet code in the RNA sequence that codes for the amino acids a
single random-mutation A-to-G switch in the right spot is enough to flip the
resulting amino acid from an aspartate to a glycine (GAU and GAC both code for
aspartic acid, and GGU and GGC both code for glycine).
Those are pretty
different beasts: aspartic acid has a polar, charged side chain, while glycine
is the no-side-chain-at-all generic amino acid.
Sheffield group was
able to match up hospitalization data with the sequencing of 453 individual
patients, and they found no correlation of hospitalization status with the
Trevor Bedford and the UW group independently checked for
this and had the same result: no apparent effect on severity of
has empirically shown the malleable and dreamlike nature of our universe.
The mutability of the universewhich quantum physics has discovered to
be one of the primary aspects of nature, not to mention of our mindsimplies
that nothing is absolute, nothing is so fundamental (particularly our state of
consciousness) that it cannot change under certain circumstances.
that weve collectively dreamed up our current situation, when enough of us wake
up to the dreamlike nature of our world and the role our consciousness plays
each moment in giving it shape and form we can, in theory and hopefully in
practice, discover that we can dream it differently.
In other words,
when we realize that we actually have a hand in creating something that isnt
serving us, it is within the realm of possibilityand within our powerto
un-create it, thereby changing the collectively shared waking dream we are
|All medical interventions, including vaccines, have risks
and benefits, stated Association of American Physicians and
Surgeons executive director, Jane M. Orient, M.D.
the duty to advise patients according to their own best judgment, and patients
have the right to decline to follow their advice.
Patients also have
the right to be fully informed and not restricted to governmentally approved
This web site is not a commercial web site and
is presented for educational purposes only.
This website defines a
new perspective with which to engage reality to which its author adheres. The
author feels that the falsification of reality outside personal experience has
forged a populace unable to discern propaganda from reality and that this has
been done purposefully by an international corporate cartel through their
agents who wish to foist a corrupt version of reality on the human race.
Religious intolerance occurs when any group refuses to tolerate religious
practices, religious beliefs or persons due to their religious ideology. This
web site marks the founding of a system of philosophy named The Truth of the
Way of the Lumière Infinie - a rational gnostic mystery religion based
on reason which requires no leap of faith, accepts no tithes, has no supreme
leader, no church buildings and in which each and every individual is
encouraged to develop a personal relation with the Creator and Sustainer
through the pursuit of the knowledge of reality in the hope of curing the
spiritual corruption that has enveloped the human spirit. The tenets of the
Truth of the Way of the Lumière Infinie are spelled out in detail on
this web site by the author. Violent acts against individuals due to their
religious beliefs in America is considered a "hate crime."
This web site
in no way condones violence. To the contrary the intent here is to reduce the
violence that is already occurring due to the international corporate cartels
desire to control the human race. The international corporate cartel already
controls the world economic system, corporate media worldwide, the global
industrial military entertainment complex and is responsible for the collapse
of morals, the elevation of self-centered behavior and the destruction of
global ecosystems. Civilization is based on coöperation. Coöperation
does not occur at the point of a gun.
American social mores and values
have declined precipitously over the last century as the corrupt international
cartel has garnered more and more power. This power rests in the ability to
deceive the populace in general through corporate media by pressing emotional
buttons which have been preprogrammed into the population through prior
corporate media psychological operations. The results have been the destruction
of the family and the destruction of social structures that do not adhere to
the corrupt international elites vision of a perfect world. Through distraction
and coercion the direction of thought of the bulk of the population has been
directed toward solutions proposed by the corrupt international elite that
further consolidates their power and which further their purposes.
views and opinions presented on this web site are the views and opinions of
individual human men and women that, through their writings, showed the
capacity for intelligent, reasonable, rational, insightful and unpopular
thought. All factual information presented on this web site is believed to be
true and accurate and is presented as originally presented in print media which
may or may not have originally presented the facts truthfully. Opinion and
thoughts have been adapted, edited, corrected, redacted, combined, added to,
re-edited and re-corrected as nearly all opinion and thought has been
throughout time but has been done so in the spirit of the original writer with
the intent of making his or her thoughts and opinions clearer and relevant to
the reader in the present time.
Fair Use Notice
This site may contain
copyrighted material the use of which has not always been specifically
authorized by the copyright owner. We are making such material available in our
efforts to advance understanding of criminal justice, human rights, political,
economic, democratic, scientific, and social justice issues, etc. We believe
this constitutes a 'fair use' of any such copyrighted material as provided for
in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C.
Section 107, the material on this site is distributed without profit to those
who have expressed a prior interest in receiving the included information for
research and educational purposes. For more information see:
www.law.cornell.edu/uscode/17/107.shtml. If you wish to use copyrighted
material from this site for purposes of your own that go beyond 'fair use', you
must obtain permission from the copyright owner.
© Lawrence Turner
All Rights Reserved